ConditionsImmune System DisordersSystemic Vasculitis
Blue Book Listing 14.03

Systemic Vasculitis

Inflammation of blood vessels causing organ damage (giant cell arteritis, ANCA-associated vasculitis, polyarteritis nodosa, etc.).

What you have to prove

Meet listing via: (1) involvement of two or more organs/body systems with one at moderate severity AND two constitutional symptoms; OR (2) repeated manifestations with marked limitation in daily activities, social functioning, or completing tasks.

Medical evidence SSA expects

Rheumatologist and specialist records, ANCA testing, biopsy confirming vasculitis, imaging of affected organs, and treatment history (corticosteroids, rituximab, cyclophosphamide).

Common misconceptions

Single-organ vasculitis with limited involvement may not qualify. Systemic ANCA-associated vasculitis with renal and pulmonary involvement typically does.

Didn't meet the listing? You can still qualify via a Medical-Vocational Allowance — SSA's determination that your residual functional capacity, combined with your age, education, and work history, leaves no jobs you can do. See our appeals guide for what to do after an initial denial.